A.D. Wrobleski

Total Synthesis of the Strychnos Alkaloid (+)-Minfiensine: Tandem Enantioselective Intramolecular Heck−Iminium Ion Cyclization

Amy B. Dounay, P. G. Humphreys, Larry E. Overman et al. · Journal of the American Chemical Society · 2008 · 211 citations · Full text

Sequential Catalytic Asymmetric Heck−Iminium Ion Cyclization:  Enantioselective Total Synthesis of the <i>Strychnos </i>Alkaloid Minfiensine

Amy B. Dounay, Larry E. Overman, A.D. Wrobleski · Journal of the American Chemical Society · 2005 · 166 citations

Facile C−N Cleavage in a Series of Bridged Lactams

Lei Yao, A.D. Wrobleski, Jennifer E. Golden et al. · Journal of the American Chemical Society · 2005 · 105 citations

Asymmetric Total Synthesis of Dendrobatid Alkaloids:  Preparation of Indolizidine 251F and Its 3-Desmethyl Analogue Using an Intramolecular Schmidt Reaction Strategy

A.D. Wrobleski, Kiran Sahasrabudhe, Jeffrey Aubé · Journal of the American Chemical Society · 2004 · 92 citations

Natural Product Synthesis, Heterocyclic, Enantioselective Synthesis +13

Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-<i>d</i>]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against <i>BRAF</i> or <i>RAS</i> Mutant Tumor Cells

James R. Henry, Michael D. Kaufman, Sheng-Bin Peng et al. · Journal of Medicinal Chemistry · 2015 · 84 citations · Full text

Kinase Inhibitors, Pharmaceutical Chemistry, Tumor Biology +20