Leon Su

Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’

Aron M. Levin, D.L. Bates, Aaron M. Ring et al. · Nature · 2012 · 538 citations · Full text

Inflammation, Cytokine, Signal Transduction +10

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

Jonathan T. Sockolosky, Eleonora Trotta, Giulia Parisi et al. · Science · 2018 · 353 citations · Full text

Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10

Robert A. Saxton, Naotaka Tsutsumi, Leon Su et al. · Science · 2021 · 195 citations · Full text

Protein microarrays for multiplex analysis of signal transduction pathways

Steven M. Chan, Joerg Ermann, Leon Su et al. · Nature Medicine · 2004 · 192 citations

Functional Genomics, Omics, Cell Biology +6

Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells

Caleb R. Glassman, Yamuna Kalyani Mathiharan, Kevin M. Jude et al. · Cell · 2021 · 167 citations · Full text

Autoimmune Disease, Il-23 Receptor, T-regulatory Cell +11