Marcia Van Ginderen

Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors

Olivia Goethals, R. Clayton, Marcia Van Ginderen et al. · Journal of Virology · 2008 · 164 citations · Full text

Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action

Dirk Jochmans, Jérôme Deval, Bart Kesteleyn et al. · Journal of Virology · 2006 · 94 citations · Full text

Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

Dirk Roymans, Sarhad Alnajjar, Michael B. Battles et al. · Nature Communications · 2017 · 90 citations · Full text

Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein

Dirk Roymans, Hendrik L. De Bondt, Éric Arnoult et al. · Proceedings of the National Academy of Sciences · 2009 · 88 citations · Full text

Viral Replication, Protein Assembly, Synthetic Virology +20

Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles

Olivia Goethals, Ann Vos, Marcia Van Ginderen et al. · Virology · 2010 · 61 citations

Minor Fold Changes, Primary Mutations, Second-generation Resistance Profiles +12