Olivia Goethals

A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction

Suzanne J. F. Kaptein, Olivia Goethals, Dominik Kiemel et al. · Nature · 2021 · 192 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors

Olivia Goethals, R. Clayton, Marcia Van Ginderen et al. · Journal of Virology · 2008 · 166 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates

Olivia Goethals, Suzanne J. F. Kaptein, Bart Kesteleyn et al. · Nature · 2023 · 124 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +15

Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles

Olivia Goethals, Ann Vos, Marcia Van Ginderen et al. · Virology · 2010 · 63 citations

Life Sciences, Pharmacotherapy, Drug Discovery +13

Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery

Franck Touret, Cécile Baronti, Olivia Goethals et al. · Antiviral Research · 2019 · 54 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17