Michael Adam

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

Sting Agonist GSK3745417 Induces Apoptosis, Antiproliferation, and Cell Death in a Panel of Human AML Cell Lines and Patient Samples

Michael Adam, Jong W. Yu, Ramona Plant et al. · Blood · 2022 · 14 citations

Manufacturing‐dependent change in biological activity of the <scp>TLR4</scp> agonist <scp>GSK1795091</scp> and implications for lipid A analog development

Neeltje Steeghs, Aaron R. Hansen, Glenn J. Hanna et al. · Clinical and Translational Science · 2022 · 13 citations · Full text

Abstract 5554: Preclinical characterization of GSK532, a novel STING agonist with potent anti-tumor activity

Jingsong Yang, Michael Adam, Jim Clemens et al. · Cancer Research · 2018 · 11 citations

Potent Anti-tumor Activity, Innate Immune System, Immunology +30