Marina Holler

ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition

Mahmoud Toulany, Minjmaa Minjgee, Mohammad Saki et al. · Cancer Biology & Therapy · 2013 · 56 citations · Full text

Pi3k Inhibitors, Tumor Cells, Cancer Biology +17

Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

Marina Holler, Astrid Grottke, Katharina Mueck et al. · PLoS ONE · 2016 · 50 citations · Full text

Akt Activity, Dna Double-strand Breaks, Mtorc1 Inhibitor Rapamycin +17

Cisplatin-mediated radiosensitization of non-small cell lung cancer cells is stimulated by ATM inhibition

Mahmoud Toulany, Julia Mihatsch, Marina Holler et al. · Radiotherapy and Oncology · 2014 · 48 citations

Atm Inhibition, Oncology, Radiation Therapy +8

Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells

Mahmoud Toulany, Julia Maier, Mari Iida et al. · Cell Death Discovery · 2017 · 45 citations · Full text