Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

Atsushi Enomoto, Hiroaki Kimura, Arthit Chairoungdua, +15

Nature

UrologyMolecular PhysiologyRenal FunctionRenal Urate–anion ExchangerMedicine +8

Decreased extra-renal urate excretion is a common cause of hyperuricemia

Kimiyoshi Ichida, Hirotaka Matsuo, Tappei Takada, +21

Nature Communications

Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

Takashi Sekine, Nobuaki Watanabe, Makoto Hosoyamada, +2

Journal of Biological Chemistry

Bioorganic ChemistryDrug KineticsExpression CloningCellular PharmacologyOrganic Chemistry +19

Clinical and Molecular Analysis of Patients with Renal Hypouricemia in Japan-Influence of URAT1 Gene on Urinary Urate Excretion

Kimiyoshi Ichida, Makoto Hosoyamada, Ichiro Hisatome, +4

Journal of the American Society of Nephrology

Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney

Makoto Hosoyamada, Takashi Sekine, Yoshikatsu Kanai, +1

American Journal of Physiology-Renal Physiology

Renal PathologyRenal InflammationTranslational PharmacologyMolecular PharmacologyRenal Function +22

Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters

Michio Takeda, Suparat Khamdang, Shinichi Narikawa, +5

Journal of Pharmacology and Experimental Therapeutics

Uric Acid Causes Vascular Smooth Muscle Cell Proliferation by Entering Cells via a Functional Urate Transporter

Duk‐Hee Kang, Lin Han, Xiaosen Ouyang, +12

American Journal of Nephrology

Uricosuric Action of Losartan via the Inhibition of Urate Transporter 1 (URAT 1) in Hypertensive Patients

Toshihiro Hamada, Kimiyoshi Ichida, Makoto Hosoyamada, +11

American Journal of Hypertension

Immunohistochemical Localization of Multispecific Renal Organic Anion Transporter 1 in Rat Kidney

Akihiro Tojo, Takashi Sekine, Noriko Nakajima, +4

Journal of the American Society of Nephrology

Function and Localization of Urate Transporter 1 in Mouse Kidney

Makoto Hosoyamada, Kimiyoshi Ichida, Atsushi Enomoto, +2

Journal of the American Society of Nephrology