Tappei Takada

Decreased extra-renal urate excretion is a common cause of hyperuricemia

Kimiyoshi Ichida, Hirotaka Matsuo, Tappei Takada et al. · Nature Communications · 2012 · 691 citations · Full text

Medicine, Nephrology, Physiology +11

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida et al. · Science Translational Medicine · 2009 · 435 citations

Life Sciences, Genetics, Molecular Genetics +13

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

Hirotaka Matsuo, Ken Yamamoto, Hirofumi Nakaoka et al. · Annals of the Rheumatic Diseases · 2015 · 184 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

Hirotaka Matsuo, Akiyoshi Nakayama, Masayuki Sakiyama et al. · Scientific Reports · 2014 · 163 citations · Full text

Medicine, Nephrology, Physiology +8

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

Hiroshi Miyata, Tappei Takada, Yu Toyoda et al. · Frontiers in Pharmacology · 2016 · 146 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15