Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

Vanessa E. Zannella, Alan Dal Pra, Hala Muaddi, +10

Clinical Cancer Research

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts

Miles A. Miller, Ravi A. Chandra, Michael F. Cuccarese, +8

Science Translational Medicine

Spatial and temporal mapping of heterogeneity in liposome uptake and microvascular distribution in an orthotopic tumor xenograft model

Sandra N. Ekdawi, James Stewart, Michael Dunne, +5

Journal of Controlled Release

Tumor BiologyProteinlipid InteractionLiposome UptakeBiomedical ImagingMicrovascular Distribution +9

A Mathematical Model of the Enhanced Permeability and Retention Effect for Liposome Transport in Solid Tumors

Shawn Stapleton, Michael Milosevic, Christine Allen, +4

PLoS ONE

EngineeringExtracellular MicrovesiclesBiomedical EngineeringLipid MovementCellular Physiology +15

Radiation and Heat Improve the Delivery and Efficacy of Nanotherapeutics by Modulating Intratumoral Fluid Dynamics

Shawn Stapleton, Michael Dunne, Michael Milosevic, +7

ACS Nano

NanoparticlesNanotherapeuticsEngineeringImmunologyBiomedical Engineering +14

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation

Shawn Stapleton, Michael Milosevic, Ian F. Tannock, +2

Journal of Controlled Release

Interstitial Fluid PressureIntra-tumoral RelationshipBiological MicroenvironmentsBiofluid DynamicPathology +11

Tumor perfusion imaging predicts the intra-tumoral accumulation of liposomes

Shawn Stapleton, Christine Allen, Melania Pintilie, +1

Journal of Controlled Release

Oncologic ImagingBiomedical ImagingExtracellular MicrovesiclesTumor MicroenvironmentTumor Perfusion +1

Real-time high dynamic range laser scanning microscopy

Claudio Vinegoni, Christine Leon Swisher, Paolo Fumene Feruglio, +4

Nature Communications

A Spinal Cord Window Chamber Model for In Vivo Longitudinal Multimodal Optical and Acoustic Imaging in a Murine Model

Sarah A. Figley, Yonghong Chen, Azusa Maeda, +10

PLoS ONE

Tissue EngineeringEngineeringBiomedical EngineeringSpinal DisorderOrthopaedic Surgery +18

Acoustic and Kinetic Behaviour of Definity in Mice Exposed to High Frequency Ultrasound

Shawn Stapleton, H. Z. Goodman, Yuqing Zhou, +4

Ultrasound in Medicine & Biology

Biomedical AcousticsKinetic BehaviourEngineeringPower UltrasoundBiological Effects Of Acoustic Waves +8