Michael F. Cuccarese

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Christopher B. Rodell, Sean P. Arlauckas, Michael F. Cuccarese et al. · Nature Biomedical Engineering · 2018 · 1K citations

Nanomedicine, Tumor Immunology, Cancer Immunosurveillance +9

In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy

Sean P. Arlauckas, Christopher Garris, Rainer H. Köhler et al. · Science Translational Medicine · 2017 · 630 citations · Full text

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts

Miles A. Miller, Ravi A. Chandra, Michael F. Cuccarese et al. · Science Translational Medicine · 2017 · 227 citations

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

Michael F. Cuccarese, J. Matthew Dubach, Christina Pfirschke et al. · Nature Communications · 2017 · 167 citations · Full text

Quantitating drug-target engagement in single cells in vitro and in vivo

J. Matthew Dubach, Eunha Kim, Katherine S. Yang et al. · Nature Chemical Biology · 2016 · 88 citations · Full text

Drug Target, Drug Targeting, Medicine +8