mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

Rishi R. Goel, Mark M. Painter, Sokratis A. Apostolidis, +31

Science

Comprehensive mapping of immune perturbations associated with severe COVID-19

Leticia Kuri-Cervantes, M. Betina Pampena, Wenzhao Meng, +28

Science Immunology

ImmunologyPathologyImmunologic MechanismCovid-19 EpidemiologyImmune System +15

Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination

Rishi R. Goel, Sokratis A. Apostolidis, Mark M. Painter, +28

Science Immunology

VaccinationImmunological MemoryDistinct AntibodyVaccine DevelopmentVaccine Target +13

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

Mohamad‐Gabriel Alameh, István Tombácz, Emily Bettini, +31

Immunity

VaccinationNanomedicineCross-protectionMucosal VaccinationVaccine Development +9

New-onset IgG autoantibodies in hospitalized patients with COVID-19

Sarah E. Chang, Allan Feng, Wenzhao Meng, +45

Nature Communications

Overlap SyndromesAutoimmune DiseaseAutoantibody ProductionHumoral ResponseImmunology +8

The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans

John L. Johnson, Rebecca L. Rosenthal, James J. Knox, +21

Immunity

Autoimmune DiseaseAdaptive Immune SystemImmune Cell DevelopmentDistinct Tissue DistributionsImmunology +7

CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy

Vinodh Pillai, Kavitha Muralidharan, Wenzhao Meng, +19

Blood Advances

Cell TherapyPrior Blinatumomab TherapyMixed-phenotype Acute LeukemiaImmunologyPathology +17

An atlas of B-cell clonal distribution in the human body

Wenzhao Meng, Bochao Zhang, Gregory W. Schwartz, +12

Nature Biotechnology

Human BodyHuman CellHematologyImmunologyBlood Cell +7

Tissue adaptation and clonal segregation of human memory T cells in barrier sites

Maya M.L. Poon, Daniel P. Caron, Zicheng Wang, +12

Nature Immunology

Tissue AdaptationBarrier SitesClonal SegregationT-regulatory CellMemory +6

Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice

Edd Ricker, Michela Manni, Danny Flores-Castro, +12

Nature Communications