mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

Rishi R. Goel, Mark M. Painter, Sokratis A. Apostolidis, +31

Science

Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination

Rishi R. Goel, Sokratis A. Apostolidis, Mark M. Painter, +28

Science Immunology

VaccinationImmunological MemoryDistinct AntibodyVaccine DevelopmentVaccine Target +13

Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

Sokratis A. Apostolidis, Mihir Kakara, Mark M. Painter, +25

Nature Medicine

Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination

Mark M. Painter, Divij Mathew, Rishi R. Goel, +29

Immunity

VaccinationVaccine DevelopmentRapid InductionAdaptive Immune SystemSars-cov-2 Mrna Vaccination +9

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

Pragnesh Mistry, Shuichiro Nakabo, Liam J. O’Neil, +16

Proceedings of the National Academy of Sciences

GeneticsImmunologyPathologyImmune DysregulationInflammation +15

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, +17

Nature Immunology

ChromatinFunctional GenomicsSingle Cell SequencingMedicineGenetics +10

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

Rishi R. Goel, Mark M. Painter, Kendall A. Lundgreen, +35

Cell

VaccinationVaccine DevelopmentImmunologyThird DoseSars-cov-2 Mrna Vaccine +4

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism

Sarthak Gupta, Shuichiro Nakabo, Luz P. Blanco, +22

Proceedings of the National Academy of Sciences

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

Sarfaraz Hasni, Sarthak Gupta, Michael A. Davis, +36

Nature Communications

Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

Carmelo Carmona‐Rivera, Philip M. Carlucci, Rishi R. Goel, +7

JCI Insight

ImmunologyImmune SystemInflammatory ArthritisInflammationRheumatoid Disorder +16