Frédéric Massé

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 473 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

Asish K. Saha, Alexandria J. Schwarsin, Raphaël Roduit et al. · Journal of Biological Chemistry · 2000 · 194 citations · Full text

Life Sciences, Biochemistry, Physiology +17

A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli

Raphaël Roduit, Christopher J. Nolan, Cristina Alarcón et al. · Diabetes · 2004 · 187 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell

Raphaël Roduit, Johane Morin, Frédéric Massé et al. · Journal of Biological Chemistry · 2000 · 157 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Lysosomotropism of Basic Cathepsin K Inhibitors Contributes to Increased Cellular Potencies against Off-Target Cathepsins and Reduced Functional Selectivity

Jean‐Pierre Falgueyret, Sylvie Desmarais, Renata M. Oballa et al. · Journal of Medicinal Chemistry · 2005 · 153 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17