Iichiro Kawahara

Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data?

Kiyomi Ito, Kōji Chiba, Masato Horikawa et al. · AAPS PharmSci · 2002 · 86 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Permeability Characteristics of Tetragastrins Across Intestinal Membranes Using the Caco-2 Monolayer System: Comparison Between Acylation and Application of Protease Inhibitors

Takuya Fujita, Iichiro Kawahara, Ying‐Shu Quan et al. · Pharmaceutical Research · 1998 · 33 citations

Pharmacy, Biochemistry, Biophysics +16

Characterization of P-Glycoprotein Inhibitors for Evaluating the Effect of P-Glycoprotein on the Intestinal Absorption of Drugs

Yusuke Kono, Iichiro Kawahara, Kohei Shinozaki et al. · Pharmaceutics · 2021 · 31 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

The Impact of Breast Cancer Resistance Protein (BCRP/ABCG2) on Drug Transport Across Caco-2 Cell Monolayers

Iichiro Kawahara, Satoyo Nishikawa, Akira Yamamoto et al. · Drug Metabolism and Disposition · 2020 · 29 citations · Full text

Medicine, Oncology, Pharmacology +17

Optimization of an azetidine series as inhibitors of colony stimulating factor-1 receptor (CSF-1R) Type II to lead to the clinical candidate JTE-952

Kazutaka Ikegashira, Taku Ikenogami, Takayuki Yamasaki et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 14 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12