Sarah J. Welsh

Regulation of an <i>ATG7</i> - <i>beclin 1</i> Program of Autophagic Cell Death by Caspase-8

Li Yu, Ajjai Alva, Helen C. Su et al. · Science · 2004 · 1.2K citations

Mitophagy, Apoptosis, Immunology +17

Autophagic programmed cell death by selective catalase degradation

Li Yu, Fengyi Wan, Sudeshna Dutta et al. · Proceedings of the National Academy of Sciences · 2006 · 660 citations · Full text

Inflammation, Cell Autophagy, Mitophagy +15

The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.

Sarah J. Welsh, William Bellamy, Margaret M. Briehl et al. · PubMed · 2002 · 348 citations

Trx-1 Transfection, Immunology, Cell Death +21

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1α

Mei Yee Koh, Taly R. Spivak-Kroizman, Sara Venturini et al. · Molecular Cancer Therapeutics · 2008 · 295 citations · Full text

Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.

Sarah J. Welsh, Ryan Williams, Lynn Kirkpatrick et al. · PubMed · 2004 · 281 citations

Hypoxia-induced Hif-1alpha Levels, Antitumor Activity, Chemoprevention Strategy +20