Ryan Williams

The Absence of Mitochondrial Thioredoxin 2 Causes Massive Apoptosis, Exencephaly, and Early Embryonic Lethality in Homozygous Mice

Larisa Nonn, Ryan Williams, Robert P. Erickson et al. · Molecular and Cellular Biology · 2003 · 439 citations · Full text

Life Sciences, Developmental Biology, Genetics +13

Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling

Nathan T. Ihle, Ryan Williams, Sherry Chow et al. · Molecular Cancer Therapeutics · 2004 · 312 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1α

Mei Yee Koh, Taly R. Spivak-Kroizman, Sara Venturini et al. · Molecular Cancer Therapeutics · 2008 · 305 citations · Full text

Medicine, Oncology, Pharmacology +13

Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha.

Sarah J. Welsh, Ryan Williams, Lynn Kirkpatrick et al. · PubMed · 2004 · 281 citations

Medicine, Oncology, Pharmacology +17

The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation.

Sarah J. Welsh, Ryan Williams, Anne Birmingham et al. · PubMed · 2003 · 252 citations

Medicine, Oncology, Pharmacology +17