Jennifer J.D. Morrissette

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

Donald M. O’Rourke, MacLean P. Nasrallah, Arati Desai et al. · Science Translational Medicine · 2017 · 1.8K citations · Full text

Medicine, Immunology, Oncology +17

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons et al. · Nature · 2018 · 861 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

Marco Ruella, David M. Barrett, Saad S. Kenderian et al. · Journal of Clinical Investigation · 2016 · 555 citations · Full text

Medicine, Hematology, Oncology +16

Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non–Small Cell Lung Cancer

Charu Aggarwal, Jeffrey C. Thompson, Taylor A. Black et al. · JAMA Oncology · 2018 · 490 citations · Full text

Medicine, Genetics, Oncology +17

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia

Miriam Kim, Kyung–Rok Yu, Saad S. Kenderian et al. · Cell · 2018 · 467 citations · Full text

Life Sciences, Genetics, Hematology +15