Xiaoming Xu

Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors

Arun K. Ghosh, Kai Xi, Valerie Grum‐Tokars et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 108 citations · Full text

Peptidomimetic Sars-cov 3Clpro, Drug Discovery, Medicine +8

Potent memapsin 2 (β-secretase) inhibitors: Design, synthesis, protein-ligand X-ray structure, and in vivo evaluation

Arun K. Ghosh, Nagaswamy Kumaragurubaran, Hong Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 93 citations · Full text

Protein-ligand X-ray Structure, Medicinal Chemistry, Protein Secretion +10

Design, Synthesis, and X-ray Structure of Potent Memapsin 2 (β-Secretase) Inhibitors with Isophthalamide Derivatives as the P₂_-P₃-Ligands

Arun K. Ghosh, Nagaswamy Kumaragurubaran, Hong Lin et al. · Journal of Medicinal Chemistry · 2007 · 85 citations · Full text

Pharmaceutical Science, Peptide Science, Pharmacotherapy +21

Structure-based design of cycloamide–urethane-derived novel inhibitors of human brain memapsin 2 (β-secretase)

Arun K. Ghosh, Thippeswamy Devasamudram, Hong Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 75 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Cycloamide–urethane-derived Novel Inhibitors +11

Enantioselective Total Synthesis of Peloruside A:  A Potent Microtubule Stabilizer

Arun K. Ghosh, Xiaoming Xu, Jae‐Hun Kim et al. · Organic Letters · 2008 · 70 citations