Jennifer Cain

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

Austin Gurney, Fumiko Axelrod, Christopher J. Bond et al. · Proceedings of the National Academy of Sciences · 2012 · 625 citations · Full text

Medicine, Cancer Biology, Oncology +16

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

Jing Shan Lim, Alvaro Ibaseta, Marcus Fischer et al. · Nature · 2017 · 496 citations

Medicine, Cancer Biology, Oncology +14

Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency

Wan-Ching Yen, Marcus Fischer, Fumiko Axelrod et al. · Clinical Cancer Research · 2015 · 241 citations

Medicine, Oncology, Pharmacology +14

WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death

Marcus Fischer, Belinda Cancilla, Vincent Yeung et al. · Science Advances · 2017 · 154 citations · Full text

Medicine, Oncology, Pharmacology +17

An activated receptor tyrosine kinase, TEL/PDGFβR, cooperates with AML1/ETO to induce acute myeloid leukemia in mice

Jay L. Grisolano, Julie O’Neal, Jennifer Cain et al. · Proceedings of the National Academy of Sciences · 2003 · 132 citations · Full text

Medicine, Molecular Biology, Oncology +17