Wan-Ching Yen

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

Austin Gurney, Fumiko Axelrod, Christopher J. Bond et al. · Proceedings of the National Academy of Sciences · 2012 · 618 citations · Full text

Immunology, Cancer Biology, Wnt/β-catenin Pathway +21

DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

Timothy Hoey, Wan-Ching Yen, Fumiko Axelrod et al. · Cell stem cell · 2009 · 397 citations · Full text

Cancer Immunosurveillance, Medicine, Immunology +7

Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency

Wan-Ching Yen, Marcus Fischer, Fumiko Axelrod et al. · Clinical Cancer Research · 2015 · 239 citations

WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death

Marcus Fischer, Belinda Cancilla, Vincent Yeung et al. · Science Advances · 2017 · 154 citations · Full text

Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic <i>KRAS</i> Mutations

Marcus Fischer, Wan-Ching Yen, Ann M. Kapoun et al. · Cancer Research · 2010 · 119 citations

Kras Mutations, Oncogenic Agent, Medicine +14