Nikhil M. Urs

Distinct cortical and striatal actions of a β-arrestin–biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties

Nikhil M. Urs, Steven M. Gee, Thomas F. Pack et al. · Proceedings of the National Academy of Sciences · 2016 · 136 citations · Full text

Psychotropic Medication, Synaptic Transmission, Neurotransmitter +19

A Dopamine D1 Receptor-Dependent β-Arrestin Signaling Complex Potentially Regulates Morphine-Induced Psychomotor Activation but not Reward in Mice

Nikhil M. Urs, Tanya L. Daigle, Marc G. Caron · Neuropsychopharmacology · 2010 · 109 citations · Full text

Molecular Pharmacology, Molecular Neuroscience, Behavioral Neuroscience +11

Targeting β-arrestin2 in the treatment of<scp>l</scp>-DOPA–induced dyskinesia in Parkinson’s disease

Nikhil M. Urs, Simone Bido, Sean M. Peterson et al. · Proceedings of the National Academy of Sciences · 2015 · 105 citations · Full text

Synaptic Signaling, Social Sciences, Molecular Pharmacology +20

Deletion of GSK3β in D2R-expressing neurons reveals distinct roles for β-arrestin signaling in antipsychotic and lithium action

Nikhil M. Urs, Joshua C. Snyder, Jacob P. R. Jacobsen et al. · Proceedings of the National Academy of Sciences · 2012 · 90 citations · Full text

Psychotropic Medication, Neurotransmitter, Psychopharmacology +23

Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor

Sean M. Peterson, Thomas F. Pack, Angela D. Wilkins et al. · Proceedings of the National Academy of Sciences · 2015 · 87 citations · Full text