Silke Schmechel

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohnʼs disease and analysis of the IL17F p.His161Arg polymorphism in IBD

Julia Seiderer, Ira Elben, Julia Diegelmann et al. · Inflammatory Bowel Diseases · 2007 · 325 citations · Full text

Life Sciences, Immunology, Molecular Genetics +17

Linking genetic susceptibility to Crohnʼs disease with Th17 cell function: IL-22 serum levels are increased in Crohnʼs disease and correlate with disease activity and IL23R genotype status

Silke Schmechel, Astrid Konrad, Julia Diegelmann et al. · Inflammatory Bowel Diseases · 2007 · 189 citations · Full text

Life Sciences, Immunology, Pathobiology +17

rs1004819 Is the Main Disease-Associated IL23R Variant in German Crohn's Disease Patients: Combined Analysis of IL23R, CARD15, and OCTN1/2 Variants

Jürgen Glas, Julia Seiderer, Martin Wetzke et al. · PLoS ONE · 2007 · 132 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

The<i>ATG16L1</i>Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population

Jürgen Glas, Astrid Konrad, Silke Schmechel et al. · The American Journal of Gastroenterology · 2008 · 108 citations

Life Sciences, Genetics, Molecular Genetics +12

Loss of Toll-like Receptor 2 and 4 Leads to Differential Induction of Endoplasmic Reticulum Stress and Proapoptotic Responses in the Intestinal Epithelium under Conditions of Chronic Inflammation

Anja Messlik, Silke Schmechel, Sigrid Kisling et al. · Journal of Proteome Research · 2009 · 24 citations

Life Sciences, Immunology, Pathology +17