Jeremy Thorpe

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease

Cem Kuscu, Şevki Arslan, Ritambhara Singh et al. · Nature Biotechnology · 2014 · 795 citations

Life Sciences, Genetics, Molecular Biology +14

The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

Rachel E. Rodin, Yanmei Dou, Minseok Kwon et al. · Nature Neuroscience · 2021 · 135 citations · Full text

Life Sciences, Genetics, Neuroscience +16

Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential

Aravinda Kuntimaddi, Nicholas J. Achille, Jeremy Thorpe et al. · Cell Reports · 2015 · 127 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development

Changuk Chung, Xiaoxu Yang, Keng Ioi Vong et al. · Nature Genetics · 2023 · 111 citations · Full text

Medicine, Genetics, Molecular Genetics +16

Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability

Taejeong Bae, Liana Fasching, Yifan Wang et al. · Science · 2022 · 72 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17