Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function

Chris McDermott‐Roe, Junmei Ye, Rizwan Ahmed, +31

Nature

Cardiac MuscleCardiomyopathyMolecular PhysiologyMitochondrial FunctionBiochemistry +7

Berberine protects acute liver failure in mice through inhibiting inflammation and mitochondria-dependent apoptosis

Lulu Xu, Zheng Xia, Yinhang Wang, +7

European Journal of Pharmacology

InflammationHepatologyMitochondrial FunctionMedicineLiver Physiology +12

Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation

Dandan Chen, Zhe Li, Peiqing Bao, +9

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

InflammationNrf2 DeficiencyCardiomyopathyCardiovascular DiseasePhysiology +10

Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation

Fan Chen, Dandan Chen, Xinmei Zhao, +9

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

InflammationObesityMetabolic SyndromeNutritionBody Composition +9

EndoG Links Bnip3-Induced Mitochondrial Damage and Caspase-Independent DNA Fragmentation in Ischemic Cardiomyocytes

Jisheng Zhang, Junmei Ye, Albert Altafaj, +7

PLoS ONE

AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia

Shuai Yang, Xinmei Zhao, Hui Xu, +7

International Journal of Molecular Sciences

Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy

Fan Chen, Dandan Chen, Yubin Zhang, +8

Biochemical and Biophysical Research Communications

InflammationCytokineCardiomyopathyCardiac MuscleCardiovascular Disease +10

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

Junmei Ye, Miriam Llorian, Maria Cardona, +8

Journal of Cell Science

Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway

Junmei Ye, Maria Cardona, Marta Llovera, +2

Journal of Molecular and Cellular Cardiology

Cardiac MuscleMyocyte Enhancer Factor-2CardiomyopathyMolecular PhysiologySignal Transduction +11

AKT2 regulates development and metabolic homeostasis via AMPK-depedent pathway in skeletal muscle

Miao Chen, Caoyu Ji, Qingchen Yang, +13

Clinical Science

Metabolic RemodelingCellular PhysiologyInsulin SignalingMetabolic SyndromeSignaling Pathway +19