Janelle Holbrook

Smac mimetics and innate immune stimuli synergize to promote tumor death

Shawn T. Beug, Vera A. Tang, Eric C. LaCasse et al. · Nature Biotechnology · 2014 · 128 citations · Full text

Immune Stimuli, Cancer Immunosurveillance, Smac Mimetics +15

TWEAK and cIAP1 Regulate Myoblast Fusion Through the Noncanonical NF-κB Signaling Pathway

Emeka K. Enwere, Janelle Holbrook, Rim Lejmi-Mrad et al. · Science Signaling · 2012 · 80 citations

Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy

Neena Lala-Tabbert, Rim Lejmi-Mrad, Kristen Timusk et al. · Skeletal Muscle · 2019 · 35 citations · Full text

Ciap1 Loss, Muscle Function, Apoptosis +22

Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression

Shawn T. Beug, Stephanie J. Pichette, Martine St-Jean et al. · Molecular Therapy — Oncolytics · 2018 · 27 citations · Full text

Tumor Regression, Immunology, Immune Regulation +22

Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice

Emeka K. Enwere, Louise Boudreault, Janelle Holbrook et al. · Human Molecular Genetics · 2012 · 15 citations · Full text