Martine St-Jean

Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

Daigen Xu, Stephen J. Crocker, J. P. Doucet et al. · Nature Medicine · 1997 · 253 citations

Rat Hippocampus, Neuronal Expression, Neurophysiology +13

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics

Dan C. McManus, Charles Lefebvre, Gabriele Cherton-Horvat et al. · Oncogene · 2004 · 170 citations

Medicine, Xiap Protein Expression, Immunology +9

Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma

Shawn T. Beug, Caroline E. Beauregard, Cristin Healy et al. · Nature Communications · 2017 · 136 citations · Full text

Smac mimetics and innate immune stimuli synergize to promote tumor death

Shawn T. Beug, Vera A. Tang, Eric C. LaCasse et al. · Nature Biotechnology · 2014 · 128 citations · Full text

Immune Stimuli, Cancer Immunosurveillance, Smac Mimetics +15

Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP

Jeffrey L. Cummings, Timothy H. Ward, Eric C. LaCasse et al. · British Journal of Cancer · 2005 · 76 citations · Full text

Antisense Compound, Apoptosis Protein, Apoptosis +23