Xishan Wu

Structure-Based Discovery and Optimization of Benzo[<i>d</i>]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)

Maofeng Zhang, Yan Zhang, Ming Song et al. · Journal of Medicinal Chemistry · 2018 · 60 citations · Full text

Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer

Qiuping Xiang, Chao Wang, Tianbang Wu et al. · Journal of Medicinal Chemistry · 2021 · 47 citations · Full text

Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist

Qiu Li, Benqiang Yao, Shiting Zhao et al. · Journal of Medicinal Chemistry · 2022 · 44 citations · Full text

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer

Yan Zhang, Xishan Wu, Xiaoqian Xue et al. · Journal of Medicinal Chemistry · 2019 · 38 citations · Full text

Structure-Based Discovery and Optimization of Furo[3,2-<i>c</i>]pyridin-4(5<i>H</i>)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors

Junhua Li, Cheng Zhang, Hongrui Xu et al. · Journal of Medicinal Chemistry · 2022 · 27 citations · Full text