Qiuping Xiang

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

Junjian Wang, June X. Zou, Xiaoqian Xue et al. · Nature Medicine · 2016 · 198 citations · Full text

Medicine, Oncology, Urology +17

Discovery of Benzo[<i>cd</i>]indol-2(1<i>H</i>)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation

Xiaoqian Xue, Yan Zhang, Zhaoxuan Liu et al. · Journal of Medicinal Chemistry · 2016 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Discovery and Optimization of Benzo[<i>d</i>]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)

Maofeng Zhang, Yan Zhang, Ming Song et al. · Journal of Medicinal Chemistry · 2018 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

2-Amino-2,3-dihydro-1<i>H</i>-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

Dongsheng Zhu, Huocong Huang, Daniel M. Pinkas et al. · Journal of Medicinal Chemistry · 2019 · 61 citations · Full text

Medicine, Oncology, Pharmacology +14

Discovery and optimization of 1-(1 H -indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer

Qiuping Xiang, Chao Wang, Yan Zhang et al. · European Journal of Medicinal Chemistry · 2018 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10