Sebastian Hayes

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli, Brittany N. Lasseigne, Slavé Petrovski et al. · Science · 2015 · 972 citations · Full text

Engineering, Exome Sequencing, Genetics +18

Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells

H. Eric, Mark Verway, Radia Marie Johnson et al. · Immunity · 2019 · 395 citations · Full text

Metabolic Syndrome, Energy Metabolism, Systems Biology +15

Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization

Wen Yang, Koji Nagasawa, Christian Münch et al. · Cell · 2016 · 338 citations · Full text

Reductive Stress, Signal Transduction, Membrane Depolarization +8

Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming

Dominic G. Roy, Jocelyn Chen, Victoria Mamane et al. · Cell Metabolism · 2020 · 321 citations · Full text

Itaconate confers tolerance to late NLRP3 inflammasome activation

Monika Bambousková, Lucie Potůčková, Tomáš Paulenda et al. · Cell Reports · 2021 · 216 citations · Full text