Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Søren G. F. Rasmussen, Hee‐Jung Choi, Juan José Fung, +15

Nature

EngineeringNanomaterialsNanotechnologyNanobody-stabilized Active StateChemistry +1

The cryo-electron microscopy structure of huntingtin

Qiang Guo, Bin Huang, Jingdong Cheng, +11

Nature

Cryo-electron Microscopy StructureElectron MicroscopyMicroscopyMolecular BiologyElectron Microscope +4

Fast native-SAD phasing for routine macromolecular structure determination

Tobias Weinert, Vincent Oliéric, S. Waltersperger, +25

Nature Methods

BiochemistryStructural BioinformaticsNatural SciencesBiomolecular Structure PredictionBiomolecular Analysis +3

Crystal Structure of Bisphosphorylated IGF-1 Receptor Kinase

Alexander Pautsch, Andreas Zoephel, Horst Ahorn, +3

Structure

Crystal StructureSignal TransductionReceptor Tyrosine KinaseProtein X-ray CrystallographyMolecular Biology +3

A systematic approach to increase the efficiency of membrane protein production in cell-free expression systems

Stefan Haberstock, Christian Roos, Yvette Hoevels, +4

Protein Expression and Purification

Protein SecretionEngineeringProtein ExpressionBiochemistryMedicine +11

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

Dianfan Li, Nicole Howe, Abhiram Dukkipati, +13

Crystal Growth & Design

Proteinlipid InteractionProtein SecretionEngineeringProtein AssemblyMolecular Biology +15

Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists

Anna-Katharina Apel, R.K. Cheng, Christofer S. Tautermann, +6

Structure

Molecular PharmacologyCrystal StructureBiochemistryG Protein-coupled ReceptorMedicine +6

Crystal Structure of Glucokinase Regulatory Protein

Alexander Pautsch, N. Stadler, Adelheid Löhle, +9

Biochemistry

Crystal StructureProtein FunctionSignal TransductionGlycosylationBiochemistry +11

BIreactive: A Machine-Learning Model to Estimate Covalent Warhead Reactivity

Ferruccio Palazzesi, Markus Hermann, Marc A. Grundl, +4

Journal of Chemical Information and Modeling

Compound ReactivityDrug TargetEngineeringChemical AnalysisComputational Chemistry +15

A Fast Ab Initio Predictor Tool for Covalent Reactivity Estimation of Acrylamides

Ferruccio Palazzesi, Marc A. Grundl, Alexander Pautsch, +2

Journal of Chemical Information and Modeling

Compound ReactivityEngineeringChemical AnalysisCovalent Reactivity EstimationComputational Chemistry +15