Cian J. Lynch

p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation

Han Li, Manuel Collado, Aránzazu Villasante et al. · Cell stem cell · 2012 · 156 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

Cian J. Lynch, Raquel Bernad, Ana Martínez‐Val et al. · Nature Cell Biology · 2020 · 65 citations

Life Sciences, Genetics, Molecular Biology +16

Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency

Cian J. Lynch, J Milner · Oncogene · 2006 · 58 citations

Life Sciences, Genetics, Molecular Genetics +12

SIRT1 Undergoes Alternative Splicing in a Novel Auto-Regulatory Loop with p53

Cian J. Lynch, Zahid H. Shah, Simon J. Allison et al. · PLoS ONE · 2010 · 49 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells

Irène Aksoy, Cloé Rognard, Anaïs Moulin et al. · Stem Cell Reports · 2020 · 43 citations · Full text

Life Sciences, Biology, Developmental Biology +17