Cian J. Lynch

p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation

Han Li, Manuel Collado, Aránzazu Villasante et al. · Cell stem cell · 2012 · 154 citations · Full text

Transcriptional Regulation, Lineage Plasticity, Developmental Biology +11

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

Cian J. Lynch, Raquel Bernad, Ana Martínez‐Val et al. · Nature Cell Biology · 2020 · 63 citations · Full text

Induced Pluripotent Stem Cell, Developmental Biology, Signal Transduction +11

Loss of one p53 allele results in four-fold reduction of p53 mRNA and protein: a basis for p53 haplo-insufficiency

Cian J. Lynch, J Milner · Oncogene · 2006 · 57 citations

P53 Haplo-insufficiency, Genome Instability, Natural Sciences +7

SIRT1 Undergoes Alternative Splicing in a Novel Auto-Regulatory Loop with p53

Cian J. Lynch, Zahid H. Shah, Simon J. Allison et al. · PLoS ONE · 2010 · 49 citations · Full text

Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells

Irène Aksoy, Cloé Rognard, Anaïs Moulin et al. · Stem Cell Reports · 2020 · 42 citations · Full text

Low Chimeric Competence, Premature Differentiation Account, Genetics +17