Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

Katrien De Bock, Sandra Schoors, Anna Kuchnio, +39

Cell

Molecular PhysiologyBioengineering ModelPfkfb3-driven GlycolysisVascular BiologyMetabolic Remodeling +4

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Julián Aragonés, Martin Schneider, Katie Van Geyte, +43

Nature Genetics

BiochemistryRedox RegulatorPhysiologyHypoxia ToleranceHypoxia (Medicine) +7

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

Steve Stegen, Kjell Laperre, Guy Eelen, +16

Nature

Cartilage DegenerationCollagen SynthesisMatrix BiologyMedicineCell Biology +3

Impaired Local Production of Proresolving Lipid Mediators in Obesity and 17-HDHA as a Potential Treatment for Obesity-Associated Inflammation

Angelika Neuhofer, Maximilian Zeyda, Daniel Mascher, +8

Diabetes

Obesity-associated InflammationOxidative StressObesityMetabolic SyndromeInflammation +18

Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function

Murtaza M. Tambuwala, Eoin P. Cummins, Colin R. Lenihan, +12

Gastroenterology

InflammationMucosal ImmunologyImmunologyGastroenterologyPathology +8

Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia

Thomas Schmidt, Behzad Kharabi Masouleh, Sonja Loges, +25

Cancer Cell

Hematological MalignancyImatinib-resistant Bcr-abl1+ LeukemiaImmunologyMedicineCell Biology +3

Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

Martin Schneider, Katie Van Geyte, Peter Fraisl, +18

Gastroenterology

BiochemistryReperfusion InjuryMedicineLiver PhysiologyCell Death +5

Mouse Very Long-chain Acyl-CoA Synthetase 3/Fatty Acid Transport Protein 3 Catalyzes Fatty Acid Activation but Not Fatty Acid Transport in MA-10 Cells

Zhengtong Pei, Peter Fraisl, Johannes Berger, +3

Journal of Biological Chemistry

Ma-10 CellsFatty AcidsAutophagyEndogenous Acsvl3Oxysterol +14

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

Angel Sandoval, Peter Fraisl, Elsa Arias‐Barrau, +4

Archives of Biochemistry and Biophysics

Metabolic SyndromeSignal TransductionFatty Acid TraffickingBiochemistryOmega-3 Fatty Acid +8

Carbohydrate Metabolism Is Perturbed in Peroxisome-deficient Hepatocytes Due to Mitochondrial Dysfunction, AMP-activated Protein Kinase (AMPK) Activation, and Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Suppression

Annelies Peeters, Peter Fraisl, Sjoerd A.A. van den Berg, +8

Journal of Biological Chemistry