Steve Stegen

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

Ilaria Elia, Matteo Rossi, Steve Stegen et al. · Nature · 2019 · 308 citations · Full text

Breast Oncology, Medicine, Breast Cancer Cells +11

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

Kateřina Rohlenová, Jermaine Goveia, Melissa García‐Caballero et al. · Cell Metabolism · 2020 · 308 citations · Full text

Angiogenesis, Developmental Biology, Single Cell Sequencing +13

HIF-1α metabolically controls collagen synthesis and modification in chondrocytes

Steve Stegen, Kjell Laperre, Guy Eelen et al. · Nature · 2019 · 288 citations · Full text

Cartilage Degeneration, Collagen Synthesis, Matrix Biology +5

Lipid availability determines fate of skeletal progenitor cells via SOX9

Nick van Gastel, Steve Stegen, Guy Eelen et al. · Nature · 2020 · 219 citations · Full text

Developmental Biology, Lipid Synthesis, Skeletal Progenitor Cells +8

HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

Steve Stegen, Nick van Gastel, Guy Eelen et al. · Cell Metabolism · 2016 · 175 citations · Full text

Redox Signaling, Developmental Biology, Cell Death +7