Eoin P. Cummins

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 3.8K citations · Full text

Inflammation, Cytokine, Inflammatory Disease +10

Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity

Eoin P. Cummins, Edurne Berra, Katrina M. Comerford et al. · Proceedings of the National Academy of Sciences · 2006 · 755 citations · Full text

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

Eoin P. Cummins, Fergal Seeballuck, Stephen J. Keely et al. · Gastroenterology · 2007 · 399 citations · Full text

Inflammation, Mucosal Immunology, Biochemistry +8

MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia

Ulrike Brüning, Luca Cerone, Zoltán Neufeld et al. · Molecular and Cellular Biology · 2011 · 290 citations · Full text

Immunology, Hypoxia-inducible Factor 1α, Hif Activation +18

Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function

Murtaza M. Tambuwala, Eoin P. Cummins, Colin R. Lenihan et al. · Gastroenterology · 2010 · 199 citations · Full text

Inflammation, Mucosal Immunology, Immunology +10