Concepedia

Helen R. Broom

HR

7

Publications

376

Citations

7

H-Index

2014

Active since

Affiliations

University of Waterloo(Current)

Hospital for Sick Children

University of Toronto

Helen R. Broom is an author at University of Waterloo specializing in protein assembly, analytical ultracentrifugation, and protein folding.

Top concepts

Publications per year

2014–2016

7

Publications

7

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways

Ashok Sekhar, Jessica Rumfeldt, Helen R. Broom et al. · eLife · 2015 · 111 citations · Full text

ALS-linked misfolded SOD1 species have divergent impacts on mitochondria

Sarah Pickles, Sabrina Semmler, Helen R. Broom et al. · Acta Neuropathologica Communications · 2016 · 67 citations · Full text

Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR spectroscopy

Ashok Sekhar, Jessica Rumfeldt, Helen R. Broom et al. · Proceedings of the National Academy of Sciences · 2016 · 58 citations · Full text

Destabilization of the dimer interface is a common consequence of diverse <scp>ALS</scp>‐associated mutations in metal free <scp>SOD1</scp>

Helen R. Broom, Jessica Rumfeldt, Kenrick A. Vassall et al. · Protein Science · 2015 · 49 citations · Full text

Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts

Colleen Doyle, Jessica Rumfeldt, Helen R. Broom et al. · Biochemistry · 2016 · 39 citations

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