Helen R. Broom - Concepedia

Author

Helen R. Broom

University of Waterloo

Also Known As

Broom, Helen R., Helen R Broom, Helen R. Broom

Publications

433

Citations

H-Index

Concepts

All Affiliations

University of Waterloo Hospital for Sick Children University of Toronto

About

Helen R. Broom is an author at University of Waterloo specializing in protein assembly, analytical ultracentrifugation, and protein folding.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	56
2	Natural Sciences	2	2	56
3	Biochemistry	2	2	56
4	Chemistry	2	2	56
5	Molecular Biology	2	2	56

Helen R. Broom

Publications

376

Citations

H-Index

Page 1

	Year	Citations
Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways Ashok Sekhar, Jessica Rumfeldt, Helen R. Broom, eLife	2015	111
ALS-linked misfolded SOD1 species have divergent impacts on mitochondria Sarah Pickles, Sabrina Semmler, Helen R. Broom, Acta Neuropathologica Communications	2016	67
Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR spectroscopy Ashok Sekhar, Jessica Rumfeldt, Helen R. Broom, Proceedings of the National Academy of Sciences	2016	58
Destabilization of the dimer interface is a common consequence of diverse <scp>ALS</scp>‐associated mutations in metal free <scp>SOD1</scp> Helen R. Broom, Jessica Rumfeldt, Kenrick A. Vassall, Protein Science	2015	49
Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts Colleen Doyle, Jessica Rumfeldt, Helen R. Broom, Biochemistry Amide Chemical ShiftsProtein AssemblyMolecular BiologyChemistryAnalytical Ultracentrifugation	2016	39
Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis Helen R. Broom, Jessica Rumfeldt, Elizabeth M. Meiering Essays in Biochemistry	2014	35
Combined Isothermal Titration and Differential Scanning Calorimetry Define Three-State Thermodynamics of fALS-Associated Mutant Apo SOD1 Dimers and an Increased Population of Folded Monomer Helen R. Broom, Kenrick A. Vassall, Jessica Rumfeldt, Biochemistry Protein AssemblyDifferential Scanning CalorimetryFolded MonomerMolecular BiologyExperimental Thermodynamics	2015	17

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