Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS

Kenrick A. Vassall, Helen R. Stubbs, Heather A. Primmer, +8

Proceedings of the National Academy of Sciences

Protein AssemblyMolecular BiologySoluble AggregatesAnalytical UltracentrifugationCu/zn Superoxide Dismutase +17

Equilibrium Thermodynamic Analysis of Amyotrophic Lateral Sclerosis-Associated Mutant Apo Cu,Zn Superoxide Dismutases^,

Kenrick A. Vassall, Peter B. Stathopulos, Jessica Rumfeldt, +2

Biochemistry

Protein AssemblyMolecular BiologyNeurochemical BiomarkersChemical BiologyRedox Biology +15

Identification of Multiple Phosphorylation Sites on Maize Endosperm Starch Branching Enzyme IIb, a Key Enzyme in Amylopectin Biosynthesis

Amina Makhmoudova, Declan Williams, Dyanne Brewer, +10

Journal of Biological Chemistry

Destabilization of the dimer interface is a common consequence of diverse <scp>ALS</scp>‐associated mutations in metal free <scp>SOD1</scp>

Helen R. Broom, Jessica Rumfeldt, Kenrick A. Vassall, +1

Protein Science

The Effects of Threonine Phosphorylation on the Stability and Dynamics of the Central Molecular Switch Region of 18.5-kDa Myelin Basic Protein

Kenrick A. Vassall, Kyrylo Bessonov, Miguel De Avila, +2

PLoS ONE

Substitutions mimicking deimination and phosphorylation of 18.5-kDa myelin basic protein exert local structural effects that subtly influence its global folding

Kenrick A. Vassall, Vladimir V. Bamm, Andrew D. Jenkins, +5

Biochimica et Biophysica Acta (BBA) - Biomembranes

Global FoldingProtein FoldingMolecular BiologyProtein MisfoldingCytoskeleton +4

Thermodynamic Analysis of the Disorder-to-α-Helical Transition of 18.5-kDa Myelin Basic Protein Reveals an Equilibrium Intermediate Representing the Most Compact Conformation

Kenrick A. Vassall, Andrew D. Jenkins, Vladimir V. Bamm, +1

Journal of Molecular Biology

Equilibrium Intermediate RepresentingThermodynamic AnalysisProtein AssemblyBiophysicsProtein Folding +10

The proline-rich region of 18.5 kDa myelin basic protein binds to the SH3-domain of Fyn tyrosine kinase with the aid of an upstream segment to form a dynamic complex<i>in vitro</i>

Miguel De Avila, Kenrick A. Vassall, Graham Smith, +2

Bioscience Reports

Molecular BiologySynaptic SignalingCellular PhysiologyChemical Shift ChangeFuzzy Mbp Complex +18

Combined Isothermal Titration and Differential Scanning Calorimetry Define Three-State Thermodynamics of fALS-Associated Mutant Apo SOD1 Dimers and an Increased Population of Folded Monomer

Helen R. Broom, Kenrick A. Vassall, Jessica Rumfeldt, +4

Biochemistry

Protein AssemblyDifferential Scanning CalorimetryFolded MonomerMolecular BiologyExperimental Thermodynamics +18

Folding and Association of Thermophilic Dimeric and Trimeric DsrEFH Proteins: Tm0979 and Mth1491

Céline Galvagnion, Martin T. J. Smith, Aron Broom, +6

Biochemistry

Protein AssemblyBiomolecular Structure PredictionStructural BioinformaticsMolecular BiologyProtein Refolding +14