Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs

Jun-ichi Jinno, Naoki Kamada, Masateru Miyake, +7

Journal of Controlled Release

Poorly Water-soluble DrugParticle Size ReductionPharmacological StudyMedicineBeagle Dogs +2

Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle

Takao Mitsui, Hiroyuki Azuma, Masakazu Nagasawa, +4

Journal of Neurology

Mitochondrial MyopathyMitochondrial BiogenesisMitochondrial FunctionMitochondrial DysfunctionPhysiology +1

In vitro–in vivo correlation for wet-milled tablet of poorly water-soluble cilostazol

Jun-ichi Jinno, Naoki Kamada, Masateru Miyake, +7

Journal of Controlled Release

Medicinal ChemistryPharmaceutical ScienceWet-milled TabletMedicineBioanalysis +7

Chitosan Oligomers as Potential and Safe Absorption Enhancers for Improving the Pulmonary Absorption of Interferon-α in Rats

Keigo Yamada, Masaaki Odomi, Naoki Okada, +2

Journal of Pharmaceutical Sciences

Lung InflammationMedicineImmunologyPulmonary PharmacologySafe Absorption Enhancers +3

In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms

R. Abbas, Chun P. Chow, Nicholas Browder, +6

Human & Experimental Toxicology

Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation

S Kudo, Masaaki Odomi

European Journal of Clinical Pharmacology

Reductive StressMolecular PharmacologyBiochemistryMedicineNatural Sciences +11

Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: Utilization of polyamines and bile acids

Masateru Miyake, Takanori Minami, Masao Hirota, +5

Journal of Controlled Release

Pharmaceutical ScienceMedicineDigestive TractDrug AbsorptionPharmacology +3

Suppression of the Bitterness of Enteral Nutrients Using Increased Particle Sizes of Branched-Chain Amino Acids (BCAAs) and Various Flavours: a Taste Sensor Study

Yohko Miyanaga, Junji Mukai, T. Mukai, +2

Chemical and Pharmaceutical Bulletin

Novel oral absorption system containing polyamines and bile salts enhances drug transport via both transcellular and paracellular pathways across Caco-2 cell monolayers

Fuyuki Mukaizawa, Koji Taniguchi, Masateru Miyake, +4

International Journal of Pharmaceutics

Pharmaceutical ScienceParacellular PathwaysBiochemistryCaco-2 Cell MonolayersMedicine +6

Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial disease

Takao Mitsui, Yoshifumi Umaki, Masakazu Nagasawa, +6

Acta Neuropathologica

Mitochondrial MyopathyMitochondrial DamageMitochondrial FunctionMitochondrial DynamicMitochondrial Therapy +7