Mike Wood

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 442 citations · Full text

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

Andrew J. Massey, D.S. Williamson, Helen Browne et al. · Cancer Chemotherapy and Pharmacology · 2009 · 327 citations · Full text

Medicine, Apoptosis, Cell Death +7

Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design

D.S. Williamson, Jenifer Borgognoni, Alexandra Clay et al. · Journal of Medicinal Chemistry · 2009 · 222 citations · Full text

Protein Chemistry, Medicinal Chemistry, Protein Function +13

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Paul A. Brough, Xavier Barril, Jenifer Borgognoni et al. · Journal of Medicinal Chemistry · 2009 · 173 citations · Full text