Kwok Ho Lam

Massively parallel de novo protein design for targeted therapeutics

Aaron Chevalier, Daniel‐Adriano Silva, Derrick R. Hicks et al. · Nature · 2017 · 477 citations · Full text

Natural Sciences, Computational Biology, Structure-based Drug Design +8

Structural basis for recognition of frizzled proteins by <i>Clostridium difficile</i> toxin B

Peng Chen, Liang Tao, Tianyu Wang et al. · Science · 2018 · 128 citations · Full text

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Guorui Yao, Sicai Zhang, Stefan Mahrhold et al. · Nature Structural & Molecular Biology · 2016 · 114 citations · Full text

Biochemistry, Natural Sciences, Botulinum Neurotoxin +5

Structure of the full-length Clostridium difficile toxin B

Peng Chen, Kwok Ho Lam, Zheng Liu et al. · Nature Structural & Molecular Biology · 2019 · 97 citations · Full text

Microbial Toxin, Toxinology, Bacteriology +5

Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

Zheng Xu, So Fun Chau, Kwok Ho Lam et al. · Biochemical Journal · 2006 · 68 citations · Full text