Guorui Yao

Massively parallel de novo protein design for targeted therapeutics

Aaron Chevalier, Daniel‐Adriano Silva, Derrick R. Hicks et al. · Nature · 2017 · 477 citations · Full text

Natural Sciences, Computational Biology, Structure-based Drug Design +8

Structural basis of agrin–LRP4–MuSK signaling

Yinong Zong, Bin Zhang, Shenyan Gu et al. · Genes & Development · 2012 · 172 citations · Full text

Synaptic Transmission, Molecular Biology, Synaptic Signaling +18

Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity

Kwangkook Lee, Shenyan Gu, Lei Jin et al. · PLoS Pathogens · 2013 · 122 citations · Full text

Toxinology, Protein Assembly, Glycobiology +19

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A

Guorui Yao, Sicai Zhang, Stefan Mahrhold et al. · Nature Structural & Molecular Biology · 2016 · 114 citations · Full text

Biochemistry, Natural Sciences, Botulinum Neurotoxin +5

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

Xinxin Li, Yiqian Liu, Qiuyang Zheng et al. · Neuroscience Letters · 2013 · 41 citations · Full text

Protein Secretion, Signal Transduction, Biochemistry +8