Joan Zugay-Murphy

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293) - an initial glance of the viral DNA binding platform 1 1Edited by I. A. Wilson

Zhongguo Chen, Youwei Yan, Sanjeev Munshi et al. · Journal of Molecular Biology · 2000 · 103 citations

Virus Structure, Viral Replication, X-ray Structure +13

Development of thioquinazolinones, allosteric Chk1 kinase inhibitors

Antonella Converso, Timothy J. Hartingh, R. M. Garbaccio et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 74 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +6

Discovery of 1-Amino-5<i>H</i>-pyrido[4,3-<i>b</i>]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders

Jongwon Lim, Brandon M. Taoka, Ryan D. Otte et al. · Journal of Medicinal Chemistry · 2011 · 73 citations · Full text

Janus Kinase 2, Jak-stat Pathway Mediates, Pharmacotherapy +19

Only a Small Fraction of Purified Hepatitis C RNA-Dependent RNA Polymerase Is Catalytically Competent:  Implications for Viral Replication and in Vitro Assays

Steven S. Carroll, Vinod Sardana, Zhucheng Yang et al. · Biochemistry · 2000 · 58 citations

Viral Replication, Vitro Assays, Rna Template +17

Identification of MK-944a:  A Second Clinical Candidate from the Hydroxylaminepentanamide Isostere Series of HIV Protease Inhibitors

Bruce D. Dorsey, Colleen M. McDonough, Stacey L. McDaniel et al. · Journal of Medicinal Chemistry · 2000 · 55 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +17