Yuqian Yan

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation

Pingzhao Zhang, Dejie Wang, Yu Zhao et al. · Nature Medicine · 2017 · 298 citations · Full text

Bet Protein Stabilization, Medicine, Cancer Cell Biology +9

RAD21 Mutations Cause a Human Cohesinopathy

Matthew A. Deardorff, Jonathan J. Wilde, Melanie Albrecht et al. · The American Journal of Human Genetics · 2012 · 267 citations · Full text

Rad21 Mutations Cause, Genetic Disorder, Genetics +4

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression

Xin Jin, Donglin Ding, Yuqian Yan et al. · Molecular Cell · 2018 · 259 citations · Full text

Cancer Immunosurveillance, Signal Transduction, Cell Regulation +12

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

Xin Jin, Yuqian Yan, Dejie Wang et al. · Molecular Cell · 2018 · 170 citations · Full text

Tumor Biology, Cell Regulation, Medicine +6

Destruction of DNA‐Binding Proteins by Programmable Oligonucleotide PROTAC (O'PROTAC): Effective Targeting of LEF1 and ERG

Jingwei Shao, Yuqian Yan, Donglin Ding et al. · Advanced Science · 2021 · 114 citations · Full text

Programmable Oligonucleotide Protac, Molecular Biology, Oligonucleotide-based Protac +16