V. Koneti Rao

Immune dysregulation in human subjects with heterozygous germline mutations in <i>CTLA4</i>

Hye Sun Kuehn, Weiming Ouyang, Bernice Lo et al. · Science · 2014 · 823 citations

Immunodeficiencies, Genetics, Immunology +21

Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

Bernice Lo, Kejian Zhang, Wei Lü et al. · Science · 2015 · 664 citations

Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency

C. Lucas, Hye Sun Kuehn, Fang Zhao et al. · Nature Immunology · 2013 · 647 citations · Full text

T Cell Senescence, Signal Transduction, Cell Regulation +7

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Joshua D. Milner, Tiphanie P. Vogel, Lisa R. Forbes et al. · Blood · 2014 · 544 citations · Full text

Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcεRI or FcγRI

Arnold S. Kirshenbaum, Cem Akin, Yalin Wu et al. · Leukemia Research · 2003 · 501 citations

Cell Therapy, Medicine, Mast Cell Disorder +7