Ralph André

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

Maria Björkqvist, Edward J. Wild, Jenny Thiele et al. · The Journal of Experimental Medicine · 2008 · 629 citations · Full text

Novel Pathogenic Pathway, Immune Activation Detectable, Immune Activation +22

HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation

Ulrike Träger, Ralph André, Nayana Lahiri et al. · Brain · 2014 · 178 citations · Full text

An exploratory double‐blind, randomized clinical trial with selisistat, a <scp>SirT1</scp> inhibitor, in patients with <scp>H</scp>untington's disease

Sigurd D. Süßmuth, Salman Haider, G. Bernhard Landwehrmeyer et al. · British Journal of Clinical Pharmacology · 2014 · 161 citations · Full text

Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

Andreas Weiss, Ulrike Träger, Edward J. Wild et al. · Journal of Clinical Investigation · 2012 · 146 citations · Full text

Immunology, Immune Regulation, Cell Death +21

FAN1 modifies Huntington’s disease progression by stabilizing the expanded <i>HTT</i> CAG repeat

Robert Goold, Michael Flower, Davina J. Hensman Moss et al. · Human Molecular Genetics · 2018 · 145 citations · Full text