David J. A. Bridewell

Bis(phenazine-1-carboxamides):  Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs

Julie A. Spicer, Swarna A. Gamage, Gordon W. Rewcastle et al. · Journal of Medicinal Chemistry · 2000 · 110 citations

Identification of human reductases that activate the dinitrobenzamide mustard prodrug PR-104A: A role for NADPH:cytochrome P450 oxidoreductase under hypoxia

Christopher P. Guise, Anderson T. Wang, Anke Theil et al. · Biochemical Pharmacology · 2007 · 87 citations

Reductive Stress, Prodrug Pr-104a, Biochemistry +9

Differential actions of aclarubicin and doxorubicin: the role of topoisomerase I.

David J. A. Bridewell, Graeme J. Finlay, Bruce C. Baguley · PubMed · 1997 · 50 citations

Drug Exposure Assays, Medicinal Fungi, Chemical Biology +16

Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)

Simon Fung, Haiyan Wang, Petr Tomek et al. · Bioorganic & Medicinal Chemistry · 2013 · 29 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +9

Natural Product-Inspired Pyranonaphthoquinone Inhibitors of Indoleamine 2,3-Dioxygenase-1 (IDO-1)*

David J. A. Bridewell, Jonathan Sperry, Jason R. Smith et al. · Australian Journal of Chemistry · 2012 · 21 citations