Jacqueline A.M. Smith

RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers

Robert J. Nichols, Franziska Haderk, Carlos Stahlhut et al. · Nature Cell Biology · 2018 · 407 citations · Full text

Ras-driven Cancers, Tumor Biology, Mutant Braf- +9

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Matthew Holderfield, Bianca J. Lee, Jingjing Jiang et al. · Nature · 2024 · 268 citations · Full text

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

Jingjing Jiang, Lingyan Jiang, Benjamin J. Maldonato et al. · Cancer Discovery · 2024 · 231 citations · Full text

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

Christopher J. Schulze, Kyle J. Seamon, Yulei Zhao et al. · Science · 2023 · 203 citations · Full text

Leukotriene Receptor Antagonists and Synthesis Inhibitors Reverse Survival in Eosinophils of Asthmatic Individuals

Elaine Lee, T. Robertson, Jacqueline A.M. Smith et al. · American Journal of Respiratory and Critical Care Medicine · 2000 · 163 citations

Inflammation, Asthma, Allergy +13