Jeffrey W. Cramer

In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life.

John R. Cirrito, Patrick C. May, Mark Odell et al. · PubMed · 2003 · 426 citations · Full text

Vivo Assessment, Social Sciences, Alzheimer's Disease +18

<i>In Vivo</i>Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

John R. Cirrito, Patrick C. May, Mark Odell et al. · Journal of Neuroscience · 2003 · 406 citations · Full text

Amyloid-β Metabolism, Isf Aβ Half-life, Social Sciences +20

3-(4-Chloro-2-Morpholin-4-yl-Thiazol-5-yl)-8-(1-Ethylpropyl)-2,6-Dimethyl-Imidazo[1,2-<i>b</i>]Pyridazine: A Novel Brain-Penetrant, Orally Available Corticotropin-Releasing Factor Receptor 1 Antagonist with Efficacy in Animal Models of Alcoholism

Donald R. Gehlert, Andrea Cippitelli, Annika Thorsell et al. · Journal of Neuroscience · 2007 · 242 citations · Full text

Psychopharmacology, Pharmacotherapy, Experimental Pharmacology +20

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

Linda M. Rorick‐Kehn, Jeffrey M. Witkin, Michael A. Statnick et al. · Neuropharmacology · 2013 · 148 citations

Psychoactive Drug, Psychiatry, Functional Selectivity +7

Advancement of Imidazo[1,2-<i>a</i>]pyridines with Improved Pharmacokinetics and nM Activity vs. <i>Mycobacterium tuberculosis</i>

Garrett C. Moraski, Lowell D. Markley, Jeffrey W. Cramer et al. · ACS Medicinal Chemistry Letters · 2013 · 111 citations · Full text