Francis Burrows

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

Adeela Kamal, Lia Thao, John Sensintaffar et al. · Nature · 2003 · 1.4K citations

Drug Target, G Protein-coupled Receptor, Medicine +10

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

Chad A. Dickey, Adeela Kamal, Karen Lundgren et al. · Journal of Clinical Investigation · 2007 · 628 citations · Full text

Signal Recognition, Molecular Biology, Alzheimer's Disease +19

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

Anthony G. Uren, Lee H. Wong, Miha Pakusch et al. · Current Biology · 2000 · 526 citations · Full text

Chromatin, Chromosome Dynamics, Cell Division +11

Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy.

Francis Burrows, Elaine J. Derbyshire, Pier Luigi Tazzari et al. · PubMed · 1995 · 336 citations

Endothelial Cells, Immunology, Endoglin Expression +17

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

Szymon Kłossowski, Hongzhi Miao, Katarzyna Kempińska et al. · Journal of Clinical Investigation · 2019 · 223 citations · Full text

Npm1-mutated Models, Hematological Malignancy, Systems Biology +13