Dirk Kostrewa

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

Liudmila Andreeva, Björn Hiller, Dirk Kostrewa et al. · Nature · 2017 · 483 citations

Chromatin, Nucleic Acid Chemistry, Chromatin Structure +15

Novel Inhibitors of DNA Gyrase:  3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening

Hans-Joachim Boehm, Markus Boehringer, Daniel Bur et al. · Journal of Medicinal Chemistry · 2000 · 378 citations

Drug Target, Biochemistry, Hit Validation +15

The mechanism of ammonia transport based on the crystal structure of AmtB of <i>Escherichia coli</i>

Lei Zheng, Dirk Kostrewa, Simon Bernèche et al. · Proceedings of the National Academy of Sciences · 2004 · 326 citations · Full text

Crystal Structure, Biochemistry, Ammonium Transport Proteins +15

RNA polymerase II–TFIIB structure and mechanism of transcription initiation

Dirk Kostrewa, Mirijam E. Zeller, Karim‐Jean Armache et al. · Nature · 2009 · 310 citations · Full text

Transcriptional Regulation, Natural Sciences, Medicine +5

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex

Sebastian Eustermann, Kevin Schall, Dirk Kostrewa et al. · Nature · 2018 · 273 citations · Full text

Chromatin, Chromatin Structure, Biochemistry +9