Michelle A. Camerino

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer

Shikhar Sharma, Chi‐Yeh Chung, Sean Uryu et al. · Cell chemical biology · 2023 · 69 citations · Full text

Medicine, Oncology, Pharmacology +17

Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4

Kevin R. W. Ngoei, Christopher G. Langendorf, Naomi X.Y. Ling et al. · Cell chemical biology · 2018 · 56 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Crystal structures of human ENPP1 in apo and bound forms

Matthew L. Dennis, Janet Newman, Olan Dolezal et al. · Acta Crystallographica Section D Structural Biology · 2020 · 44 citations · Full text

Medicine, Molecular Biology, Oncology +12

The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface

Michelle A. Camerino, Nan Zhong, Aiping Dong et al. · MedChemComm · 2013 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation

Shikhar Sharma, Jay H. Chung, Sean Uryu et al. · Cancer Research · 2021 · 14 citations · Full text

Medicine, Molecular Biology, Oncology +16